BUCHWALD'S ATROPHY

\bˈʌt͡ʃwə͡ldz ˈatɹəfi], \bˈʌt‍ʃwə‍ldz ˈatɹəfi], \b_ˈʌ_tʃ_w_əl_d_z ˈa_t_ɹ_ə_f_i]\

Definitions of BUCHWALD'S ATROPHY

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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