BERLE NODIFLORE

\bˈɜːl nˈɒdɪflˌɔː], \bˈɜːl nˈɒdɪflˌɔː], \b_ˈɜː_l n_ˈɒ_d_ɪ_f_l_ˌɔː]\
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1846 - Medical lexicon: a dictionary of medical science
By Robley Dunglison

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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