ADAH ISAACS MENKEN

\ɐdˈɑːɹ ˈa͡ɪsəks mˈɛŋkən], \ɐdˈɑːɹ ˈa‍ɪsəks mˈɛŋkən], \ɐ_d_ˈɑː_ɹ ˈaɪ_s_ə_k_s m_ˈɛ_ŋ_k_ə_n]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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